To validate the prognostic accuracy of CENPA for overall survival in glioma patients, we examined its prognostic association across five independent glioma datasets: TCGA (LGG+GBM) (n = 703), CGGA mRNAseq693 (n = 693), CGGA mRNAseq325 (n = 325), CGGA mRNA-array301 (n = 301), and ICGC (pediatric brain tumor) (n = 120). Here, CENPA is linked to central nervous system cancer.