KEGG pathway enrichment revealed that the top two pathways associated with CENPA were "DNA replication" and "Cell cycle." The top GO molecular function (MF) was related to ATPase activities, the top GO cellular component (CC) was chromosome regions, and the top GO biological processes (BP) included "organelle fusion," "mitotic nucleus division," and "nucleus division." These GO-enriched terms were all linked to cancer proliferation and the cell cycle (S2D Fig). Here, DNAH8 is linked to cancer.