Incidences of abnormal indicators of D-dimer, Blood pH, C-reactive protein (CRP), Ferritin, and TropT are usually associated with patients with comorbidities such as Diabetes, obesity, coronary artery disease, hypertension, atrial fibrillation, and chronic heart failure (CHF), cancer, previous angina, peripheral arterial disease, previous myocardial infarction (MI), chronic kidney disease (CKD), cerebrovascular disease, and chronic obstructive pulmonary disease (COPD), HIV and many more51,52. This evidence concerns the gene CRP and atrial fibrillation.