ILC2s secrete cytokines associated with the Th2 population, including IL-4, IL-5, IL-9, and IL-13, to promote tissue repair and maintain tissue homeostasis.278 RORγt regulates ILC3s development and ILC3s produce IL-17, IL-22, TNF, and granulocyte-macrophage-colony-stimulating factor.70,279–282 ILC3s are important for defending extracellular bacteria and are associated with autoimmune diseases.67,283–285. This evidence concerns the gene IL17A and autoimmune disease.