Moreover, the scRNA-seq profile of anti-neutrophil cytoplasmic antibody (ANCA)-associated glomerulonephritis (GN) showed higher infiltration levels of TRM17 cells than health.106 Genes associated with T cell activation, proliferation, and cytokine production were upregulated in the TRM cells derived from ANCA-associated GN.106 Therefore, CD8+TRM cells at least partially contribute to kidney autoimmune diseases. Here, CD8A is linked to ganglioneuroma.