Immunohistochemistry of the primary bronchial tumor lesion and of pleural recurrence enabled us to assign the SCLC to the NEUROD1-dominant subtype (13) (strong NEUROD1 expression, partly moderate ASCL1 expression, YAP1- and POU2F3-negative; Supplemental Fig. 4), which had already been shown to correlate on a molecular level with high SSTR2 expression (3). Here, YAP1 is linked to small cell lung carcinoma.