Interestingly, these findings on CVIDid versus CVIDio subgroups were highly similar to CVID-IgA versus CVID + IgA subgroups, while these patient groups are only 66% overlapping (36 CVIDio + IgA + 25 CVIDid-IgA / the total cohort of 93 CVID patients). The gene discussed is CD79A; the disease is common variable immunodeficiency.