INS and Insulin resistance: Recent studies have confirmed that desynchronization of the circadian rhythm is linked to an increased risk of insulin resistance (IR) and related diseases [2, 5].Previous studies conducted to examine the association between SW and IR by the homeostasis model assessment of IR (HOMA-IR) index proposed that SW may be related to IR [6, 7].However, the low practicality and poor reproducibility of the HOMA-IR index [8], in addition to the requirement for insulin measurement [9]limit the ability of the use of this index in primary clinical practice as well as in epidemiological studies.