GSTA4 and colorectal carcinoma: Zou, et al. reported that E. faecalis at a low MOI can inhibit apoptosis in RAW264.7 cells.53 A recent study showed a role of Gsta4 in the regulation of oligodendrocyte apoptosis.54 However, our studies revealed that inactivation of GSTA4 in human CRC cells had no influence on chemotherapeutic agent-induced apoptosis.14 Whether the loss of Gsta4 promotes apoptosis in E. faecalis-infected macrophages remains uncertain, which is an ongoing project in our laboratory.