MUC5AC and myeloid sarcoma: It is interesting that in our cohort of patients with newly diagnosed MS, we observed enrichment of Monoglobus pectinilyticus, a recently discovered pectin-degrading organism.40 This observation complements other studies that have reported an elevation of the mucin degrader Akkermansia muciniphila in MS.4,9 Future studies will be needed to determine whether dysregulation of such microbes contributes to the “leaky gut” phenomenon observed in MS.35,41