NACC1 and neoplasm: Nucleus accumbens-associated protein 1 (Nac1) is a repressor protein that mediates the interactions between transcription factors with an essential role in carcinoma tumour growth.28 In targeting Nac1 homodimerization two separate sections were explored as initial sequences: 12FGNSILECLNEQR24 (3) and 44HRAVLAASSSYFRDLFN60 (4) with 3 showing weak binding in an FP assay (KD = 360 μM) and 4 showing no binding (Fig. 4C).