Bioinformatics analysis revealed positive correlations between SERPINE1 and various immune cells within the tumor microenvironment (TME), including Eosinophils, Tgd, Macrophages, Th1 cells, Th2 cells, iDC, Neutrophils, and Tcm cells, while Cytotoxic cells, B cells, pDC, and NK56 bright cells exhibited negative correlations with SERPINE1. The gene discussed is ABCA1; the disease is neoplasm.