DEFA3 and myeloid sarcoma: RRMS neutrophils did indeed have higher levels of cathelicidin (normalized intensity mean 2.8 × 108 in MS vs 1.7 × 108 in HD, P = 0.0048), alpha defensin 1 (mean 2.6 × 106 vs 1.1 × 106, P = 0.0024) and alpha defensin 3 (mean 3.99 × 109 vs 1.76 × 109, P 0.034) compared to healthy neutrophils.