Cross‐comparison of TAK, LV‐GCA, and biopsy‐proven C‐GCA revealed highly similar plasma proteomic profiles, with 26 shared DAPs including interleukin 6 (IL‐6), monocyte/macrophage‐related proteins (CCL7, CSF1), tissue remodeling proteins (TIMP1, TNC), and novel associations (TNFSF14, IL‐7R). Here, IL6 is linked to temporal arteritis.