AFP and neoplasm: Although the definition of high-risk recurrent metastatic factors varies among studies, high-risk factors for postoperative evaluation typically include: tumor rupture, tumor diameter > 5 cm, multiple tumors, satellite nodes, microvascular invasion, macrovascular invasion, lymph node metastasis, high preoperative AFP levels, impaired liver function, positive or narrow margins, and Edmondson grade III-IV tissue differentiation.