The SNaPshot technique meets all the necessary conditions for the detection of mutations in the KRAS and NRAS genes in patients with CRC, especially for middle- or low-income countries that may not have access to new sequencing technologies, since it allows several SNPs to be detected in a single reaction, decreasing costs and execution times, in addition, it is sensitive with low amounts of DNA, even degraded DNA, since it is effective with short length sequences [50-80pb] [5, 39]. Here, KRAS is linked to colorectal carcinoma.