Briefly, we have highlighted some of the strongest relations with the HCC risk include Naive CD4+ T cell Absolute Count (OR = 1.134, 95% CI = 1.032– 1.247, p = 0.009), CD40 on monocytes (OR = 0.897, 95% CI = 0.820– 0.981, p = 0.018) and HLA DR on CD33+ HLA DR+ CD14dim (OR = 0.860, 95% CI = 0.752– 0.983, p = 0.027) (Figure 3). This evidence concerns the gene CD4 and hepatocellular carcinoma.