gbCNP−/− mice fed a CDAA diet exhibited increased hepatic fibrosis, inflammatory/immune cell infiltration into the liver, evidence of hepatocellular damage (i.e. plasma AST and ALT concentrations), and increased spleen weight and portal vein area compared with WT littermates (Figs. 2A, B, E–H, and J–L and S3A); though, steatosis and liver size were unchanged between genotypes (Fig. 2C, D, and I). The gene discussed is GPT; the disease is Hepatic fibrosis.