SNORA37 directly binds to cap methyltransferase 1 (CMTR1) to facilitate its interaction with ELAVL1, resulting in nuclear retention and activity of ELAVL1 in regulating alternative splicing of CD44, which indicates the roles of SNORA37/CMTR1/ELAVL1 feedback loop in gastric cancer progression. The gene discussed is SNORA37; the disease is gastric cancer.