Through further comprehensive analysis of gastric cancer datasets derived from Integrated Database of CRISPR Screens (iCSDB, https://www.kobic.re.kr/icsdb/) [32] and KM-Plotter database, CMTR1, ESF1, and NVL were chosen as potential SNORA37-binding proteins essential for both cellular viability and patients’ survival of gastric cancer (Fig. 4b). The gene discussed is CMTR1; the disease is gastric cancer.