SNORD17 deletion promotes the cytoplasmic translocation of nucleophosmin 1 (NPM1) and MYB binding protein 1a (MYBBP1A) to facilitate their interaction with mouse 3T3 cell double minute 2 (MDM2) or p300 essential for p53 stabilization, thereby suppressing tumor progression [36]. This evidence concerns the gene EP300 and neoplasm.