TMC8 and infection: To examine whether DNA vaccination could treat a persistent MmuPV1 infection, Tmc6-/- (n = 18), Tmc8-/- (n = 9) FVB mice (females, aged 3 months) were first challenged intravaginally with 5.1x1011 vge MmuPV1, and an additional cohort of 10 wildtype FVB mice (females) was not challenged.