(C) The upSet plot shows the degree of overlap across cell types of the variants; ranked from the most common variant (red) – rs61888800 from BDNF locus, a well-known 5' untranslated region variant of this gene that is associated with anti-depression and therapeutic response (Licinio et al., 2009; Colle et al., 2015) – appeared in 39 cell types, to the group of variants (grey) which appeared in only one cell type. The gene discussed is BDNF; the disease is major depressive disorder.