Achondroplasia is an autosomal dominant genetic disorder caused by heterozygous gain-of-function variants of the fibroblast growth factor receptor 3 (FGFR3) gene with greater than 99% having a pathogenic variant in the same nucleotide regardless of ethnicity (ie, c.1138G > A or c.1138G > C; (p.Gly380Arg)). Here, FGFR3 is linked to achondroplasia.