High expression of FRα has been detected in ovarian cancer, breast cancer, endometrial cancer, cervical cancer, lung cancer, colon cancer and mesotheliomas (Dindere et al., 2022; Gonzalez et al., 2024; Norton et al., 2020; Saito et al., 2023; Shi et al., 2022; Varaganti et al., 2023). Here, FOLR1 is linked to ovarian carcinoma.