RECQL4 and neoplasm: Since for SKCM only expression data from tumour and metastatic tissue are available in the TCGA database, we also used GTEx data for normal tissue from the GEPIA2 web tool to compare RECQL4 expression in tumour versus healthy skin and in this case observed a significant upregulation of RECQL4 driven by tumour development (Figure 5B, p < .001).