Moreover, previous research has indicated a correlation between elevated RECQL4 levels, tumour aggressiveness and poor prognosis in a subset of cancer types, comprising prostate,14 breast,15 ovarian,16 gastric,17, 18 oesophageal cancer19, colon adenocarcinoma,20 hepatocellular carcinoma21 and glioma.22 This evidence concerns the gene RECQL4 and neoplasm.