VPS33B and pulmonary fibrosis: Finally, we showed that in idiopathic pulmonary fibrosis (IPF), a life-threatening disease with unknown trigger/mechanism where lung tissue is replaced with collagen fibrils, integrin α11 subunit, and VPS33B are located at the invasive fibroblastic focus where collagen fibril rapidly accumulates (Herrera et al., 2019); IPF fibroblasts also have elevated endocytic recycling of exogenous collagen-I, despite having similar collagen-I expression level to normal fibroblasts.