PPARA and diabetic cardiomyopathy: While for KEGG enrichment, 18 MRGs were mainly enriched in pathways including PPAR signaling pathway, diabetic cardiomyopathy, thermogenesis, etc. The PPI networks revealed complex interactions between the 18 MRGs and proteins predominantly involved in mitochondrial respiratory chain complex IV, glycolytic process, citrate cycle (TCA cycle), regulation of pyruvate dehydrogenase (PDH) complex, pseudouridine synthesis, RNA polymerases D, superoxide anion generation, as illustrated in Figure S1.