The results indicated that the low‐risk group had greater enrichment in the proteoglycans in cancer, PI3K‐Akt signaling pathway, regulation of actin cytoskeleton, TGF‐beta signaling pathway and transcriptional mis‐regulation in cancer, while exhibiting lower enrichment in the ATP‐dependent chromatin remodeling and spliceosome. Here, TGFB1 is linked to cancer.