Notably, the TGF-β signaling pathway was significantly altered in HF patients, with 7 miRNAs (miR-192-5p, miR-122-5p, miR-146a-5p, miR-629-3p, miR-483-3p, miR-378c, and miR-21-5p) targeting 27 genes. The gene discussed is TGFB1; the disease is hydrops fetalis.