However, when we applied conditional medium from OV_ANGPTL4 fibroblasts to PANC-1 pancreatic cancer cells, we observed a significant increase in cancer cell proliferation (Figure 10A), migration (Figures 10B and 10C), and would healing (Figures 10D and 10E), compared to medium from control fibroblasts. This evidence concerns the gene ANGPTL4 and familial pancreatic carcinoma.