VWF and deep vein thrombosis: The study found that both platelets and endothelial cells appear to be activated by chemotherapy.20 The study by Vandyet al. reported that in a study conducted on all inpatients and outpatients for 3 years, 159 patients with confirmed DVT had statistically significant levels of Soluble P Selectin, D-dimer, CRP, and von Willebrand factor.