The three incident T2D clusters showed significant differences across metabolic research parameters, including fasting plasma glucose and insulin, 2‐h post‐load plasma insulin, fasting plasma triglycerides, HDL‐cholesterol, VLDL‐cholesterol, adiponectin, and leptin (Figure 2C–H, Table‐1). This evidence concerns the gene ADIPOQ and type 2 diabetes mellitus.