In NSCLC, gene rearrangements involving ALK, ROS1, and RET occur in approximately 3%–7%, 1%–2%, and 1%–2% of cases, respectively, while NTRK fusions are rarer, occurring in less than 1% of cases [24, 25, 26, 27, 28, 29, 30]. The gene discussed is RET; the disease is non-small cell lung carcinoma.