The expression of DNMT1, G9a, and UHRF1 (scores 3 + versus 2 + , 1 + and 0) in tumor was correlated with various clinicopathological variables: sex, tumor site (pancreatic head vs. body/tail), pT stage (pT1, pT2, pT3), pN stage (pN0, pN1, pN2), vascular invasion, perineural invasion, tumor grade (G3 vs. G1/G2) and need of adjuvant therapy. The gene discussed is DNMT1; the disease is neoplasm.