The following KEGG pathways showed significant enrichment in the brown(miCases) module: long term potentiation, axon guidance, regulation of the actin cytoskeleton, ErbB signalling pathway, T cell receptor signalling pathway, neurotrophin signalling pathway, MAPK signalling pathway, choline metabolism in cancer, FoxO signalling pathway, glioma, cGMP-PKG signalling pathway, renal cell carcinoma, cellular senescence, and B cell receptor signalling pathway. The gene discussed is BDNF; the disease is central nervous system cancer.