Gastric cancer cells were found to overexpress the taurine transporter SLC6A6, thereby depleting taurin in the tumor microenvironment and induce taurine deficiency in CD8+ T cells, leading to ER stress and immune exhaustion.510 Finally, several studies have also revealed potential druggable immune targets for selective digestive cancers. The gene discussed is SLC6A6; the disease is gastric cancer.