This TREM-1-mediated enhancement of the proinflammatory immune response has been demonstrated in several models of infection, inflammatory bowel disease [20, 22, 23], septic shock [24], and sepsis syndrome [25], it is also critical in some sterile inflammatory conditions, including atherosclerosis [26], postischemic myocardial remodeling [27], abdominal aortic aneurysm [28], and rheumatoid arthritis [29]. This evidence concerns the gene TREM1 and abdominal aortic aneurysm.