Ma et al’s study on clear cell renal cell carcinoma reveals a strong correlation between CRP levels and the expression of autophagy-related protein 9B (ATG9B), a regulator of the autophagy process that, when upregulated, promotes cancer cell survival and proliferation.[30] These findings collectively underscore the pivotal role of CRP in EC development. The gene discussed is ATG9B; the disease is clear cell renal carcinoma.