These pathways were mainly connected with the AGE–RAGE signaling pathway in diabetic complications, pathways in cancer, lipid and atherosclerosis, colorectal cancer, fluid shear stress, atherosclerosis, prostate cancer, p53 signaling pathway, cellular senescence, FoxO signaling pathway, and PI3K–Akt signaling pathway. This evidence concerns the gene AKT1 and colorectal cancer.