This list was further filtered through a triple-negative breast cancer (TNBC) scRNA-Seq dataset (31) by applying a stringent criteria selection (i.e., high expression restricted to the macrophage cluster; Supplemental Table 5), leading to 4 genes: SPP1, APOC1, FCER1G, and MMP9. The gene discussed is SPP1; the disease is triple-negative breast carcinoma.