These findings are supported by single-cell RNA sequencing (scRNA-Seq) data retrieved from the Human Colon Cancer Atlas (c295), which reveals higher expression of PIK3CA, MTOR, and RPS6KB1 in tumor cells compared with healthy cells (Figure 8, C and D, and Supplemental Figure 11). The gene discussed is RPS6KB1; the disease is malignant colon neoplasm.