The most widely studied murine model of Duchenne muscular dystrophy (DMD) is the Dmdmdx mutant mouse (mdx) (1, 2), which is characterized by the absence of the protein dystrophin with consequent severe muscle pathology including membrane damage, Ca2+ dysregulation, elevated reactive oxygen species (ROS), and aberrant cell signaling (3). This evidence concerns the gene DMD and Duchenne muscular dystrophy.