CCL7 and colorectal carcinoma: Using a taxonomy-guided approach, we performed targeted abundance analysis of fusobacterial Fic gene families and Fap2 homologs, which revealed significant co-occurrence patterns in clinical samples (R2,control = 0.144, P = 7.3 × 10−35; R2,adenoma = 0.136, P = 2.1 × 10−8; R2,CRC = 0.401, P = 2.3 × 10−102; Fig. 2a, rug scatterplot).