STC1 and cancer: We next explored the association of STC1 and key clinical and biological parameters with OS in patients from the CORRECT trial based on a multivariable Cox regression model including the following variables as covariates: treatment, age, ECOG performance status at baseline, liver metastases at baseline, number of metastatic sites, primary cancer site, KRAS mutational status, time since initial diagnosis, and the categorical biomarkers STC1, TIE2, and LDH (optimized cut-offs).