ALK and non-small cell lung carcinoma: Since the first description of ALK gene rearrangements in NSCLC by Soda in 2007, there has been a wide range of ALK incidence noted in the literature (<2%–13%; refs. 25, 26), and the incidence of ALK alterations of 7.08% (n = 43/607) observed in this study fits within the previously observed range.