These metabolic changes, including body weight loss (Fig. S4F), improved glucose tolerance (Fig. S4G), insulin sensitivity (Fig. S4H) and hyperinsulinemia (Fig. S4I) and reductions in the blood TG (Fig. S4J) levels were still significantly different between genotypes regardless of the housing conditions and were comparable between separately housed and cohoused mice of the same genotype. The gene discussed is INS; the disease is Hyperinsulinemia.