A network pharmacology analysis by Zhao et al. [47] showed that GSTM1, TGFB1, TP53, GSTP1, and RB1 are the key genes of curcumin's anti-HCC effect, in which the elevated mRNA expression levels of GSTM1, TP53, and RB1 indicate that the overall survival of HCC is further prolonged. The gene discussed is RB1; the disease is hepatocellular carcinoma.