SHE was diagnosed in the proband and his brother in this study but has not been reported in previous families with PAK3, although epilepsy phenotypes have not always been well described (Table 1).2, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26. The gene discussed is PAK3; the disease is sleep-related hypermotor epilepsy.