ANXA5 and posterior cortical atrophy: The Annexin V-FITC/PI assay revealed a significant increase in apoptosis after AGD1 knockdown in docetaxel-treated PCa cells (22.03 ± 1.72% vs. 13.53 ± 0.71% in PC3 cells; 27.57 ± 1.30% vs. 14.83 ± 0.45% in DU145 cells), while AGD1 overexpression significantly decreased apoptosis (9.70 ± 0.60% vs. 13.60 ± 0.99% in PC3 cells; 9.67 ± 0.78% vs. 14.73 ± 0.57% in DU145 cells) (Fig. 3C and D).