Annexin V-FITC/PI assay showed a decreased percentage of apoptotic PCa cells incubated with AGD1-OE-PCSCs-exos (7.58 ± 0.16% vs. 13.50 ± 0.40% in PC3; 8.21 ± 0.27% vs. 14.43 ± 0.45% in DU145) and an increased percentage with shAGD1-PCSCs-exos under 20 nM docetaxel (20.03 ± 0.65% vs. 13.50 ± 0.40% in PC3; 24.50 ± 0.82% vs. 14.43 ± 0.45% in DU145) (Fig. 2E and F). This evidence concerns the gene ANXA5 and posterior cortical atrophy.