SST and early-onset autosomal dominant Alzheimer disease: Due to its widespread distribution, SST interacts with multiple targets through a family of five somatostatin receptor (SSTR) subtypes (SSTR1‐5), thereby exerting a broad spectrum of biological effects.[14] Dysregulation of the SST‐SSTR signaling pathway has been implicated in various diseases, with studies indicating that memory loss in patients with Alzheimer's disease (AD) is associated with deficits in SST function.[15]