Moreover, compared with blood EVs from the HCs, blood EVs isolated from the patients with cirrhosis exerted proinflammatory effects on macrophages, as indicated by increased p‐STING and p‐TBK1 protein levels, ISG expression, and proinflammatory factor levels (Figure 6K–N; Figure S11, Supporting Information). Here, STING1 is linked to Cirrhosis.