Additionally, IF staining revealed downregulation in the expression of degeneration‐ (ACAN) and senescence‐ (MMP3 and p16INK4a) related biomarkers in H2O2‐treated NPCs following VN‐siSer treatment, suggesting its therapeutic effect in rescuing ROS‐induced NPC senescence (Figure S24C,D, Supporting Information). This evidence concerns the gene CDKN2A and nasopharyngeal carcinoma.