Furthermore, upregulation of macrophage mannose receptor 1-like 4 involved in lymphocyte trafficking (95), and cysteinyl leukotriene receptors (CYSLTR1 and CYSLTR2) (96, –, 98) that enhance vascular permeability to leukocyte and eosinophil migration during airway inflammation in humans and mouse models, also indicated a distinct environment for immune cell migration in the trachea of the ∆gG-ILTV-infected TOCs compared with the CSW-1 ILTV-infected TOCs. The gene discussed is CYSLTR1; the disease is inflammatory response.