THBS1 and infection: Using glycoprotein G (gG)-deficient (∆gG-ILTV) and glycoprotein-G-expressing strains of ILTV in different in vitro, ex vivo, and in vivo infection models, Coppo et al. demonstrated the influence of gG in the transcription of select cytokine and chemokine genes, underscoring the impact of this glycoprotein in inflammation, virulence, and balance of immune responses (17) during different stages of host response to ILTV.