Notably, among patients with iCCA, IDH1 and FGFR2 alterations were mutually exclusive (log2OR: −2.70, Q < 0.001); the FGFR2 gene was frequently co‐mutated with BAP1 (log2OR: 1.55, Q < 0.001), while the IDH1 gene was commonly co‐mutated with PBRM1 (log2OR: 1.09, Q < 0.001) (Figure 1A). The gene discussed is PBRM1; the disease is infantile convulsions and choreoathetosis.